The 2PawsUp mission is to save animals on death row in high-kill shelters, provide any needed medical care, and find loving, safe forever homes for each and every animal. 2PawsUp also seeks to raise the awareness of the overpopulation and high euthanasia rates in North Carolina and to stop the endless cycle of shelter animals by spaying and neutering.

PO Box 37790
Raleigh, NC 27627

Phone: Not Available

AARF aids homeless and helpless cats and dogs in the greater Winston-Salem area; providing rescue and adoption services, information, and education while encouraging the human/animal bond. As an organization it is supported by dozens of volunteers who work endlessly to implement the mission of the Animal Adoption and Rescue Foundation.

311 Harvey Street
Winston-Salem, NC 27103

Phone: (336) 768-7387

The mission of the APS of Durham is to educate the public about the humane care, treatment and well-being of all animals, to help stop pet overpopulation through the promotion of spay/neuter programs, and to find suitable adoptive homes for the animals in our care.

2117 E. Club Blvd
Durham, NC 27704

Phone: (919) 560 -0640

Our purpose is to provide medical assistance, foster homes, and adoption services to previously lost, abandoned, abused, or neglected animals in Wake County, NC and the surrounding counties. Our mission is to educate this disposable society in which we live that every life should be valued and cherished and is directly linked to human responsibility and commitment.

P.O. Box 5305
Cary, NC 27512

Phone: (919) 661-1722

The Cabarrus Pets Society is a 501 (c) 3 non-profit organization whose purpose is to make our community a better place by rescuing unwanted dogs. We vaccinate, spay or neuter, restore them to health, and find them loving, deserving, permanent homes. Our mission is to prevent unwanted pets by educating the public about responsible pet ownership to include the importance of spaying and neutering.

PO BOX 5042
CONCORD, NC 28027

Phone: (704) 786-7729

At Carolina Animal Rescue and Adoption (CARA) we are dedicated to finding permanent and loving families for the homeless dogs and cats of North Carolina. CARA began rescuing homeless animals from across N.C. in April 2003.

42 Deep River Road
Sanford, NC 27330

Phone: (919) 774-9433

The mission of Chatham Animal Rescue and Education (CARE) is to promote the health and safety of all cats and dogs in Chatham County. CARE strives to teach by example, to be a resource to the community and local government, and to provide foster care for animals until they can be adopted into permanent homes.

Post Office Box 610
Pittsboro, NC 27312

Phone: (919) 542-5757

Fayetteville Animal Protection Society, Inc. (FAPS) is a No-Kill, non-profit animal shelter supported by volunteers, grants and individual contributions. With your help, FAPS continues as one of the “most progressive” shelters in the state of NC. Additionally, FAPS has sponsored spay/neuter billboards and frequently visits classrooms giving presentations on kindness to animals.

3927 Bragg Blvd
Fayetteville, NC 28303

Phone: (910) 864-9040

The United Animal Coalition is a professional, caring organization devoted to saving the lives of lost, abandoned and surrenderd animals of Guilford County, N.C. We strive to humanely care for all the animals and work diligently to return lost animals to their owners. We are committed to making every adoption of every animal a positive, permanent experience for both the animals and the pet owner.

4525 West Wendover Avenue
Greensboro, NC 27409

Phone: (336) 297-5020

The mission of the Humane Society of Concord & Greater Cabarrus County, N. C. is to end animal suffering and cruelty, reduce overpopulation and educate the public regarding responsible animal ownership. Supporting efforts to establish a low cost spay/neuter clinic for low income families and a sanctuary for homeless animals

PO Box 5347
Concord, NC 28027

Phone: (704) 763-8550

At IAR, we believe that the welfare of animals is paramount. We feel that we can alleviate problems associated with animal overpopulation and abandonment using a 4-pronged approach (1) Rescue and adoption of unwanted and abused animals; (2) funding of spay/neuter; (3) education and outreach on animal welfare to our youngest members of the community.

Post Office Box 14232
Durham, NC 27709

Phone: (919) 403-2221

The Macon County Humane Society, established in 1968, has been and is a valuable service to the people of Macon County. The Humane Society’s purpose and mission is. To establish and maintain a shelter for the humane care of animals. To distribute literature and information relevant to the protection of animals. To feed, clean, and provide medical care for stray, lost, or injured animals

851 Lake Emory Road
Franklin, NC 28734

Phone: (828) 524-4588

Mitchell Mill Animal Hospital Rescue is dedicated rescuing, rehabilitating and adopting cats and dogs of all shapes, sizes and colors! We tend to take the more medically challenged animals into our rescue program.

4012 Mitchell Mill Road
Raleigh, NC 27616

Phone: (919) 266-8177

Moore Humane Society is a private, nonprofit organization incorporated in 1966. We are the founders of animal welfare in the Sand hills. Moore Humane Society operates the only privately funded, state licensed animal shelter in Moore County and practices "no-kill" philosophies.

P.O. Box 203
Southern Pines, NC 28388

Phone: (910) 947-2631

Our mission is to help end pet overpopulation, abandonment and neglect. We provide care and find homes for dogs of any breed, age, or medical need. We have found homes for over 2,000 dogs in the last 10 years. We hope to have this number keep growing as we strive to save these sweet souls.

PO Box 241
Harrisburg, NC 28075

Phone: Not Available

While at Saving Grace the dogs learn basic manners. We begin with the most important lessons, such as crate training and not jumping on people. Of course, it is the responsibility of the dog's new family to continue that training - including housetraining.

PO Box 1649
Wake Forest, NC 27588

Phone: (919) 518-1180

Second Chance's mission is to rescue abandoned and stray cats and dogs, provide excellent care for each pet and match each pet with the best home for its needs, in order to ensure a long lifetime of safety, love and companionship. Second Chance also encourages responsible pet ownership through education, advocacy, programs and services.

6003 Chapel Hill Road, Suite 133
Raleigh, NC 27607

Phone: (919) 851-8404

The Wake County Animal Care, Control and Adoption Center has many dogs, cats and other small animals including waiting to find loving new homes. Visit our site to learn more about pet adoption, animal health & safety, fostering, finding or reporting a lost pet and more. The Wake County Animal Center serves all of Wake County, North Carolina

820 Beacon Lake Drive
Raleigh, NC 27610

Phone: (919) 212-7387

The Watauga Humane Society maintains an exceptional shelter, despite the fact that the kennels have been pieced together over the past 24 years and are woefully inadequate to meet the need. Nevertheless, the care, health, and love offered to our animals is beyond comparison.

200 Casey Lane, Boone
Boone, NC 28607

Phone: (828) 264 -7865